Learning-related changes in response patterns of prefrontal neurons during instrumental conditioning

@article{Mulder2003LearningrelatedCI,
  title={Learning-related changes in response patterns of prefrontal neurons during instrumental conditioning},
  author={Antonius B. Mulder and Rebecca Elizabeth Nordquist and Okyay Org{\"u}t and Cyriel M. A. Pennartz},
  journal={Behavioural Brain Research},
  year={2003},
  volume={146},
  pages={77-88}
}
A crucial aspect of organizing goal-directed behavior is the ability to form neural representations of relationships between environmental stimuli, actions and reinforcement. Very little is known yet about the neural encoding of response-reward relationships, a process which is deemed essential for purposeful behavior. To investigate this, tetrode recordings were made in the medial prefrontal cortex (PFC) of rats performing a Go-NoGo task. After task acquisition, a subset of neurons showed a… CONTINUE READING
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