Learning potentiates neurophysiological and behavioral placebo analgesic responses

@article{Colloca2008LearningPN,
  title={Learning potentiates neurophysiological and behavioral placebo analgesic responses},
  author={Luana Colloca and Michele Tinazzi and Serena Recchia and Domenica Le Pera and Massimiliano Valeriani},
  journal={PAIN},
  year={2008},
  volume={139},
  pages={306-314}
}
Abstract Expectation and conditioning are supposed to be the two main psychological mechanisms for inducing a placebo response. Here, we further investigate the effects of both expectation, which was induced by verbal suggestion alone, and conditioning at the level of N1 and N2–P2 components of CO2 laser‐evoked potentials (LEPs) and subjective pain reports. Forty‐four healthy volunteers were pseudorandomly assigned to one of three experimental groups: Group 1 was tested with verbal suggestion… Expand
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