Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: Modification by cholinergic drugs

@article{Ridley1986LearningIF,
  title={Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: Modification by cholinergic drugs},
  author={R. Ridley and T. Murray and J. A. Johnson and H. Baker},
  journal={Brain Research},
  year={1986},
  volume={376},
  pages={108-116}
}
  • R. Ridley, T. Murray, +1 author H. Baker
  • Published 1986
  • Biology, Medicine
  • Brain Research
  • Five common marmosets (Callithrix jacchus) received unilateral ibotenic acid lesions of the basal nucleus of Meynert (nBM). Seven days later, choline acetyltransferase activity was significantly reduced by 50% in the frontal and temporal neocortex, 40% in the amygdala, and approximately 30% in the motor, parietal and occipital cortex in the ipsilateral hemisphere. Four marmosets receiving equivalent bilateral ibotenic acid lesions were severely impaired on new visual object discrimination… CONTINUE READING
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