Learning and memory impairment in cocaine-dependent and comorbid schizophrenic patients

  title={Learning and memory impairment in cocaine-dependent and comorbid schizophrenic patients},
  author={Mark R. Serper and Andrea Bergman and Marc L. Copersino and James C.-Y. Chou and Danielle Richarme and Robert Cancro},
  journal={Psychiatry Research},

Cognitive disparity in schizophrenics with and without cocaine dependency.

Neuropsychological functioning and age-related changes in schizophrenia and/or cocaine dependence

Neurocognitive Characteristics of Individuals With Schizophrenia and Cocaine Dependence: Comparison of Currently Dependent and Remitted Groups

Few neuropsychological differences between remitted and current dependent states across the SZ and AD groups suggest that cognitive impairment may be relatively static in these populations.

Working memory and multi-tasking in paranoid schizophrenia with and without comorbid substance use disorder.

The present study indicates severe working memory and multi-tasking deficits in schizophrenia which are, however, not exacerbated by comorbid addiction.

Working memory and depressive symptoms in patients with schizophrenia and substance use disorders

Investigating the potential differences in psychiatric symptoms and cognition between schizophrenia patients with and without substance use disorders found patients in the dual diagnosis group displayed more severe depressive symptoms and poorer strategy during the working memory task.

Neurocognition, symptomatology, and functional skills in older alcohol-abusing schizophrenia patients.

The results suggest that alcohol abuse in schizophrenia is associated with more impaired functioning across many domains, including memory impairment, negative and general psychopathology symptoms, and adaptive functions.

Inferior performance on selected neuropsychological tests in abstinent schizophrenia patients who have used cannabis

It turned out that the group of patients who used cannabis, despite the shortest duration of disease and that of addiction, and highest percentage of using atypical antipsychotics, performed worse on all cognitive tests, compared to the groups with predominant opioid or amphetamine use.

Cognitive functioning associated with stimulant use in patients with non-affective psychosis, their unaffected siblings and healthy controls

The presence of cognitive deficits associated with lifetime stimulant use is dependent on the frequency of use, with no observed deficits in infrequent users and modest negative effects in frequent users.



The nature of learning and memory impairments in schizophrenia.

Results suggest that most SC patients demonstrate a pattern of learning and memory impairments that resembles the pattern seen in patients with primary subcortical (specifically striatal) pathology.

Verbal learning and memory in schizotypal personality disorder.

It is suggested that SPD patients have a deficit in verbal learning that is similar to, although not as severe as, the impairments seen in schizophrenia.

Substance abuse and cognitive functioning in schizophrenia.

This study compares the social and cognitive functioning and the symptoms of 33 schizophrenia subjects who abuse substances with 33 nonabusing schizophrenia subjects and finds no differences in cognitive functioning.

Neuropsychological deficits in chronic cocaine abusers.

Neuropsychological test scores were correlated with lifetime amount of cocaine used, suggesting a direct relationship between cocaine abuse and cognitive impairment.

Effects of chronic cocaine abuse on memory and learning.

  • W. MittenbergS. Motta
  • Psychology
    Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
  • 1993

Significance of Cocaine History in Schizophrenia

The results suggest that the clinical presentation in schizophrenia is significantly associated with prior cocaine experience and patients with a cocaine history were found to be significantly more depressed, less socialized, and more impaired in conceptual encoding and verbal memory.

Neuropsychological impairment in chronic cocaine abusers.

In the cocaine abuser sample, neuropsychological performance was related to the amount and recency of cocaine use, suggesting a direct role of cocaine on cognitive functioning.