Learning Substrates in the Primate Prefrontal Cortex and Striatum: Sustained Activity Related to Successful Actions

@article{Histed2009LearningSI,
  title={Learning Substrates in the Primate Prefrontal Cortex and Striatum: Sustained Activity Related to Successful Actions},
  author={Mark H. Histed and Anitha Pasupathy and Earl K. Miller},
  journal={Neuron},
  year={2009},
  volume={63},
  pages={244-253}
}
Learning from experience requires knowing whether a past action resulted in a desired outcome. The prefrontal cortex and basal ganglia are thought to play key roles in such learning of arbitrary stimulus-response associations. Previous studies have found neural activity in these areas, similar to dopaminergic neurons' signals, that transiently reflect whether a response is correct or incorrect. However, it is unclear how this transient activity, which fades in under a second, influences actions… CONTINUE READING
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