Learning Distributions of Shape Trajectories from Longitudinal Datasets: A Hierarchical Model on a Manifold of Diffeomorphisms

@article{Bne2018LearningDO,
  title={Learning Distributions of Shape Trajectories from Longitudinal Datasets: A Hierarchical Model on a Manifold of Diffeomorphisms},
  author={Alexandre B{\^o}ne and Olivier Colliot and Stanley Durrleman},
  journal={2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition},
  year={2018},
  pages={9271-9280}
}
We propose a method to learn a distribution of shape trajectories from longitudinal data, i.e. the collection of individual objects repeatedly observed at multiple time-points. The method allows to compute an average spatiotemporal trajectory of shape changes at the group level, and the individual variations of this trajectory both in terms of geometry and time dynamics. First, we formulate a non-linear mixed-effects statistical model as the combination of a generic statistical model for… 

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References

SHOWING 1-10 OF 48 REFERENCES

Learning spatiotemporal trajectories from manifold-valued longitudinal data

A Bayesian mixed-effects model is proposed to learn typical scenarios of changes from longitudinal manifold-valued data, namely repeated measurements of the same objects or individuals at several points in time, to estimate a group-average trajectory in the space of measurements.

Statistical Learning of Spatiotemporal Patterns from Longitudinal Manifold-Valued Networks

A mixed-effects model to learn spatiotempo-ral patterns on a network by considering longitudinal measures distributed on a fixed graph is introduced and it is shown that the personaliza-tion of this model yields accurate prediction of maps of cortical thickness in patients.

Statistical analysis of trajectories on Riemannian manifolds: Bird migration, hurricane tracking and video surveillance

We consider the statistical analysis of trajectories on Riemannian manifolds that are observed under arbitrary temporal evolutions. Past methods rely on cross-sectional analysis, with the given

Geodesic regression of image and shape data for improved modeling of 4D trajectories

This paper presents a framework for joint image and shape regression which incorporates images as well as anatomical shape information in a consistent manner and derives a gradient descent algorithm which simultaneously estimates baseline images and shapes, location of control points, and momenta.

Statistics on the space of trajectories for longitudinal data analysis

This paper presents a novel formulation of the longitudinal data analysis problem by identifying the structural changes over time to a product Riemannian manifold endowed with a Riemanni metric and a probability measure and presents theoretical results showing that the maximum likelihood estimate of the mean and median of a Gaussian and Laplace distribution respectively on the product manifold yield the Fréchet mean and Median respectively.

Sasaki metrics for analysis of longitudinal data on manifolds

The ability of these methods to distinguish differences in shape changes in a comparison of longitudinal corpus callosum data in subjects with dementia versus healthily aging controls is demonstrated.

Riemannian Nonlinear Mixed Effects Models: Analyzing Longitudinal Deformations in Neuroimaging

This paper generalizes non-linear mixed effects model to the regime where the response variable is manifold-valued, i.e., f: Rd → M: Rd; and demonstrates the immediate benefits such a model can provide and derive the underlying model and estimation schemes and demonstrate the direct consequence of the results.

Spatiotemporal Atlas Estimation for Developmental Delay Detection in Longitudinal Datasets

The method is used to analyze the morphological evolution of 2D profiles of hominids skulls and to analyze brain growth from amygdala of autistics, developmental delay and control children.

Bayesian Mixed Effect Atlas Estimation with a Diffeomorphic Deformation Model

A diffeomorphic constraint on the deformations considered in the deformable Bayesian mixed effect template model is introduced and an extension of the model including a sparsity constraint to select an optimal number of control points with relevant positions is proposed.

Multivariate General Linear Models (MGLM) on Riemannian Manifolds with Applications to Statistical Analysis of Diffusion Weighted Images

The variational algorithm efficiently solves for multiple geodesic bases on the manifold concurrently via gradient updates and allows us to answer questions such as: what is the relationship of the measurement at voxel y to disease when conditioned on age and gender.