Learned taste aversions in children receiving chemotherapy.

@article{Bernstein1978LearnedTA,
  title={Learned taste aversions in children receiving chemotherapy.},
  author={Ilene L. Bernstein},
  journal={Science},
  year={1978},
  volume={200 4347},
  pages={
          1302-3
        }
}
  • I. Bernstein
  • Published 16 June 1978
  • Psychology, Medicine
  • Science
Children with neoplastic diseases were offered an unusual ice cream before their drug treatments. Patients experiencing gastrointestinal toxicity due to the drugs were subsequently less likely to choose that ice cream again than controls. This suggests that taste aversions induced by drug-associated symptoms may contribute to the appetite loss experienced by cancer patients. 
Food aversions in children receiving chemotherapy for cancer
Pediatric patients receiving cancer chemotherapy formed aversions to familiar foods in their usual diet when these foods were consumed prior to drug treatments. These aversions were evidently learned
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Patients on chemotherapy were less likely to display a distinct preference for any of the five concentrations of sucrose, particularly high levels, than those not on chemotherapy, and anorectics were more likely to prefer lower sweetness levels than nonanorectICS, but sweet foods constituted a greater percentage of their daily caloric intake.
Cyclophosphamide-induced disruption of umami taste functions and taste epithelium
Learned food aversions among cancer chemotherapy patients. Incidence, nature, and clinical implications
TLDR
No strong association was observed between the incidence of food aversions and treatment outcome measures, but quality of life issues warrant further consideration.
“Good Medicine Always Has a Bitter Taste”
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In 1994, Nelson et al. provided an insightful review of possible etiologies of the cancer anorexia-cachexia (AC) syndrome, which is a major cause of morbidity and mortality in cancer patients.
Food preferences of patients with cancer.
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