Leanness, smoking, and enhanced oxidative DNA damage.

  title={Leanness, smoking, and enhanced oxidative DNA damage.},
  author={Tetsuya Mizoue and Hiroshi Kasai and Tatsuhiko Kubo and Shoji Tokunaga},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  volume={15 3},
An increased risk of some forms of cancer, including lung cancer, among lean individuals has been consistent; however, there is a paucity of biological evidence supporting this relation. Subjects analyzed were 177 healthy Japanese workers who participated in a lifestyle intervention study. The levels of urinary 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative DNA damage, were measured using an automated high-pressure liquid chromatography and urinary creatinine levels were adjusted for… CONTINUE READING


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