Leaky gut – concept or clinical entity?

  title={Leaky gut – concept or clinical entity?},
  author={Eamonn M. M. Quigley},
  journal={Current Opinion in Gastroenterology},
  • E. Quigley
  • Published 1 March 2016
  • Medicine
  • Current Opinion in Gastroenterology
Purpose of review This article evaluates the current status of the gut barrier in gastrointestinal disorders. Recent findings The gut barrier is a complex, multicomponent, interactive, and bidirectional entity that includes, but is not restricted to the epithelial cell layer. Intestinal permeability, the phenomenon most readily and commonly studied, reflects just one (albeit an important one) function of the barrier that is intimately related to and interacts with luminal contents, including… 

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