• Corpus ID: 14146153

Lead pollution - a risk factor for cardiovascular disease in Asian developing countries.

@article{Iqbal2012LeadP,
  title={Lead pollution - a risk factor for cardiovascular disease in Asian developing countries.},
  author={Mohammad Perwaiz Iqbal},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2012},
  volume={25 1},
  pages={
          289-94
        }
}
  • M. Iqbal
  • Published 2012
  • Medicine
  • Pakistan journal of pharmaceutical sciences
Lead (Pb) pollution is a serious problem in the developing countries, especially in South Asia. No levels of blood Pb can be considered safe for human health. While hypertensive effects of Pb have been well studies, there are only a few studies on the relationship of Pb exposure to the development of cardiovascular disease (CVD) in the Asian developing countries. The underlying mechanism is still unclear; however, oxidative stress and hyperhomocysteinemia appear to be most plausible hypotheses… 

Figures from this paper

Analytical and Comparative Study About the Impact of Lead Homeostasis on Cardiovascular Disorders in Humans
TLDR
This is the first study carried out to elucidate the contribution of the personal habits as smoking and the physiological process as aging on lead homeostasis and deposition in different storage sites of the human body especially on the cardiovascular system in Jordanian cadavers.
ASSESSMENT OF BLOOD LEAD LEVELS AND ASSOCIATED RISK FACTORS AND OUTCOME OF LEAD POISONING AMONG A SAMPLE IN BAQUBAH CITY.
TLDR
The findings revealed that the higher mean blood lead levels in cases (generators workers) and the lowest in taxi driver revealed that there is a significant difference between World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 8, 234-247.
Obesity Influence on Lead levels in Blood and Scalp Hair among Teenage Smokers in Jordan
TLDR
Obesity and duration of smoking are playing a plausible role in increasing lead levels in blood and hair of the university students, which in turn may develop clinical manifestations after 10-20 years.
Association of Body Iron Status with the Risk of Premature Acute Myocardial Infarction in a Pakistani Population
TLDR
This study shows a positive association between total body iron status and risk of premature AMI in a Pakistani population.
Pb, Hg and Cd Concentration of Blood and Exposure-Related Factors
TLDR
Blood concentrations of heavy metals were closely related to exposure-related factors, and age, smoking, drinking alcohols, obesity, hyperlipidemia, and household income were found to be relevant.
Human Health Risk Assessment of Heavy Metals from the Agricultural Soil in South Herzegovina
Contamination of agricultural soils can present a signifi cant risk to human health through oral ingestion, particle inhalation, and dermal contact. Th e aims of this research were to determinate the
Factors associated with blood zinc, chromium, and lead concentrations in residents of the Nam Pong River in Thailand
TLDR
The blood levels of zinc, chromium, and lead were determined and the factors influencing these levels in the blood of residents of the Nam Pong River were identified to identify factors influencing the accumulation of heavy metals in the population.
Non-cancerogenic Risk to Human Health with Pb, Cu, and Zn Intake from Soil in the Area of Herzegovina
TLDR
The aim of this paper was to determine the level of heavy metals (Pb, Cu, and Zn) concentrations in the total form and by using the Hazard Quotient Index a non-cancerogenic risk to adult and children health by oral, digestive and dermal intake ofheavy metals from the soil into the body has been calculated.
Role of ALAD and VDR genotypes on the association of low blood lead level with serum uric acid and blood pressure in automobile paint workers of Karachi, Pakistan.
TLDR
The research foretells that combination of ALAD 1-2/VDR BB may play a significant role against lead induced nephrotoxicity at low BLL with continuous lead exposure.
...
...

References

SHOWING 1-10 OF 66 REFERENCES
Blood lead levels in Egyptian children: influence of social and environmental factors.
TLDR
The social variables predictive of higher lead levels in young Egyptian children are established and activities that contribute to lower levels of Pb exposure should be identified.
Role of metals ( Cadmium and lead ) in patients of hypertension and their relationship with Ischemic Heart Disease
TLDR
It is evident from the present study that from the assessment of serum, trace elements status may be indicative of pathological disorders such as hypertension with the simultaneous existence or non existence of Ischemic Heart Disease.
Non-occupational lead exposure and hypertension in Pakistani adults
TLDR
Increase in systolic blood pressure was significantly predictive with increase in blood lead levels, and body mass index and lipid profile including total cholesterol, low density lipoprotein cholesterol, high density cholesterol and triglyceride correlated with blood pressure.
Association of Blood Lead (Pb) and Plasma Homocysteine: A Cross Sectional Survey in Karachi, Pakistan
TLDR
This study showed a relationship between blood Pb and hyperhomocysteinemia in a general population of Karachi, Pakistan, and the harmful effect of Pb on cardiovascular system could be due to its association with hyper homocysteine.
Relation between blood lead levels and childhood anemia in India.
TLDR
Health agencies in India should note the association of elevated blood lead levels with anemia and make further efforts to curb lead pollution and childhood anemia.
Blood lead levels of a population group not occupationally exposed to lead in Singapore.
  • K. Neo, K. Goh, C. Şam
  • Medicine
    The Southeast Asian journal of tropical medicine and public health
  • 2000
TLDR
Using multiple regression analysis, factors significantly associated with blood lead levels were: exposure to traffic, age, age (>50 years) and active smoking, and passive smoking, exposure to recent paint work, consumption of alcohol and traditional medicine.
Blood lead levels of a population group not occupationally exposed to lead in Singapore.
TLDR
Exposure to traffic, age (>50 years), and active smoking were found to be significantly associated with blood lead levels, while passive smoking, exposure to recent paint work, consumption of alcohol and traditional medicine were found not to be significant.
Association of Body Iron Status with the Risk of Premature Acute Myocardial Infarction in a Pakistani Population
TLDR
This study shows a positive association between total body iron status and risk of premature AMI in a Pakistani population.
Association of blood lead and homocysteine levels among lead exposed subjects in Vietnam and Singapore
TLDR
Blood lead was found to be associated with homocysteine levels in this Asian sample and it is sensible to consider the probability that this relation could explain one of the mechanisms of the impact of lead on the cardiovascular system.
Low-levels of blood lead and antioxidant status
TLDR
The results reveal that even at blood lead levels as low as 14.15μg/dl ± 4.8μG/dl, there is a significant decrease in the levels of total antioxidant status.
...
...