Lead-induced genotoxicity in lymphocytes from peripheral blood samples of humans: in vitro studies.

@article{Shaik2006LeadinducedGI,
  title={Lead-induced genotoxicity in lymphocytes from peripheral blood samples of humans: in vitro studies.},
  author={Abjal Pasha Shaik and S. Jyothi Sankar and Satish Chandra Reddy and Prabhavathy G Das and K. Jamil},
  journal={Drug and chemical toxicology},
  year={2006},
  volume={29 1},
  pages={111-24}
}
Lead is a known toxicant that has been implicated in encephalopathy in children and may affect the gastrointestinal and hematopoietic and other systems in adults. In fact, lead has been shown to compete with calcium for entry into the synaptosome and induce toxic effects. The aim of the current study was to evaluate the cytotoxic and genotoxic effects of lead by using lymphocytes from human peripheral blood in vitro. The LC50 for lead nitrate as determined by Trypan blue dye exclusion technique… CONTINUE READING
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