Lead Exposure Induces Telomere Instability in Human Cells

  title={Lead Exposure Induces Telomere Instability in Human Cells},
  author={G{\'e}raldine Pottier and Muriel Viau and Michelle Ricoul and Grace Shim and Marion Bellamy and Corina Cuceu and William M. Hempel and Laure Sabatier},
  booktitle={PloS one},
Lead (Pb) is an important environmental contaminant due to its widespread use over many centuries. While it affects primarily every organ system of the body, the most pernicious effects of Pb are on the central nervous system leading to cognitive and behavioral modification. Despite decades of research, the mechanisms responsible for Pb toxicity remain poorly understood. Recent work has suggested that Pb exposure may have consequences on chromosomal integrity as it was shown that Pb exposure… CONTINUE READING
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