Le foie : un organe du système immunitaire ?

  title={Le foie : un organe du syst{\`e}me immunitaire ?},
  author={Pascal Lapierre and Fernando Alvarez},
  journal={M S-medecine Sciences},
The liver stands in a unique position between the gastrointestinal tract and systemic venous system. Its constant exposure to food antigens, bacterial products and potential pathogens through the mesenteric circulation, requires the liver to maintain tolerogenic capabilities while preserving the means to mount effective immune responses. The liver has the unique ability amongst solid organs, to activate naive CD8+ T lymphocytes in an antigen-specific manner. However, this activation can be… 
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