LdCompare: rapid computation of single- and multiple-marker r2 and genetic coverage

@article{Hao2007LdCompareRC,
  title={LdCompare: rapid computation of single- and multiple-marker r2 and genetic coverage},
  author={K. Hao and X. Di and S. Cawley},
  journal={Bioinformatics},
  year={2007},
  volume={23 2},
  pages={252-4}
}
UNLABELLED The scale of genetic-variation datasets has increased enormously and the linkage equilibrium (LD) structure of these polymorphisms, particularly in whole-genome association studies, is of great interest. The significant computational complexity of calculating single- and multiple-marker correlations at a genome-wide scale remains challenging. We have developed a program that efficiently characterizes whole-genome LD structure on large number of SNPs in terms of single- and multiple… CONTINUE READING
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