Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of Engagement


In spite of a comprehensive understanding of the schematics of T cell receptor (TCR) signaling, the mechanisms regulating compartmentalization of signaling molecules, their transient interactions, and rearrangement of membrane structures initiated upon TCR engagement remain an outstanding problem. These gaps in our knowledge are exemplified by recent data… (More)
DOI: 10.3389/fimmu.2012.00155


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