Layer-Specific Targeting of Direction-Selective Neurons in the Zebrafish Optic Tectum

@article{Gabriel2012LayerSpecificTO,
  title={Layer-Specific Targeting of Direction-Selective Neurons in the Zebrafish Optic Tectum},
  author={Jens Peter Gabriel and Chintan A Trivedi and Colette M. Maurer and Soojin Ryu and Johann H. Bollmann},
  journal={Neuron},
  year={2012},
  volume={76},
  pages={1147-1160}
}
Direction selectivity (DS) is an important neuronal property in the visual system, but how DS is generated beyond the retina remains controversial. Here, we report a close correspondence between the preferred direction (PD) and the morphology of DS cells in the optic tectum. Ca(2+) imaging in cells expressing the genetically encoded Ca(2+) indicator GCaMP3 and multiphoton-targeted patch-clamp recordings allowed us to compare structure and function in single neurons. The arbors of differently… CONTINUE READING
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