Laxative potency and acute toxicity of some anthraquinone derivatives, senna extracts and fractions of senna extracts.

@article{Hietala1987LaxativePA,
  title={Laxative potency and acute toxicity of some anthraquinone derivatives, senna extracts and fractions of senna extracts.},
  author={Pentti Hietala and Martti L. A. Marvola and Tapani Parviainen and H Lainonen},
  journal={Pharmacology & toxicology},
  year={1987},
  volume={61 2},
  pages={
          153-6
        }
}
This paper investigates the laxative effect and acute toxicity of certain fractions of senna extracts in mice. The same tests were also carried out with several pure anthraquinone derivatives common in senna pods. The results show that the laxative and toxic components of senna pods and senna extracts can be separated. The most potent laxative components, sennosides A + B and Fraction V (relative potencies 1 and 0.9 respectively), have the lowest toxicity (relative intravenous toxicities 1 and… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Similar Papers

Loading similar papers…