Latest advances in innate antiviral defence

@inproceedings{Irving2009LatestAI,
  title={Latest advances in innate antiviral defence},
  author={Aaron T. Irving and Bryan R. G. Williams},
  booktitle={F1000 biology reports},
  year={2009}
}
Recent identification of key components in the pattern recognition receptor pathway of retinoic acid-inducible gene-1-like receptors, coupled with characterisation of a new cytoplasmic DNA-sensing molecule, have led to a greater understanding of the role viral nucleic acids play in activating innate immunity. This activation of type I interferon is… CONTINUE READING