Laterality defects in the national birth defects prevention study (1998-2007): birth prevalence and descriptive epidemiology.

@article{Lin2014LateralityDI,
  title={Laterality defects in the national birth defects prevention study (1998-2007): birth prevalence and descriptive epidemiology.},
  author={Angela E. Lin and Sergey V. Krikov and Tiffany J. Riehle-Colarusso and Jaime Luis Fr{\'i}as and John Belmont and Marlene Anderka and Tal Geva and Kelly D Getz and Lorenzo D Botto},
  journal={American journal of medical genetics. Part A},
  year={2014},
  volume={164A 10},
  pages={2581-91}
}
Little is known epidemiologically about laterality defects. Using data from the National Birth Defects Prevention Study (NBDPS), a large multi-site case-control study of birth defects, we analyzed prevalence and selected characteristics in children born with laterality defects born from 1998 to 2007. We identified 517 nonsyndromic cases (378 heterotaxy, 73.1%; 139 situs inversus totalis [SIT], 26.9%) resulting in an estimated birth prevalence of 1.1 per 10,000 live births (95% confidence… CONTINUE READING

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