Laterality, region, and type of motor dysfunction correlate with cognitive impairment in Parkinson's disease.

@article{Williams2007LateralityRA,
  title={Laterality, region, and type of motor dysfunction correlate with cognitive impairment in Parkinson's disease.},
  author={Lindsy N. Williams and Paul J. Seignourel and Gregory P. Crucian and Michael S. Okun and Ramon L. Rodriguez and F. M. Skidmore and Paul S Foster and Charles E. IV Jacobson and Janet Romrell and Dawn Bowers and Hubert H. Fernandez},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2007},
  volume={22 1},
  pages={
          141-5
        }
}
We studied the relationship between two screening cognitive measures and off motor Unified Parkinson's Disease Rating Scale (UPDRS) scores in 108 Parkinson's disease patients. Multiple regressions were conducted to examine the UPDRS subscores' unique contributions to cognitive function. When including bradykinesia, rigidity, and postural/gait instability subscores, only bradykinesia predicted Mini Mental Status Examination (MMSE), normalized beta = -0.57, t(104) = -3.31, P < 0.01, and Dementia… CONTINUE READING

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