Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.

@article{Cheesman2005LateralisationOS,
  title={Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.},
  author={Amanda Cheesman and Roger A. Barker and Simon J. G. Lewis and Trevor W. Robbins and Adrian M. Owen and David J. Brooks},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2005},
  volume={76 9},
  pages={1204-10}
}
OBJECTIVES The aetiology of the cognitive changes seen in Parkinson's disease (PD) is multifactorial but it is likely that a significant contribution arises from the disruption of dopaminergic pathways. This study aimed to investigate the contribution of the dopaminergic system to performance on two executive tasks using (18)F-6-fluorodopa positron emission tomography ((18)F-dopa PET) in PD subjects with early cognitive changes. METHODS 16 non-demented, non-depressed PD subjects were… CONTINUE READING