Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion.

Abstract

Integrins are cell membrane adhesion receptors involved in morphogenesis, immunity, tissue healing, and metastasis. A central, yet unresolved question regarding the function of integrins is how these receptors regulate both their conformation and dynamic nanoscale organization on the membrane to generate adhesion-competent microclusters upon ligand binding… (More)
DOI: 10.1073/pnas.1116425109

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Cite this paper

@article{Bakker2012LateralMO, title={Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion.}, author={Gert Jan Bakker and Christina Eich and Juan A. Torreno-Pina and Ruth Diez-Ahedo and Gemma Perez-Samper and Thomas S. van Zanten and Carl G. Figdor and Alessandra Cambi and Mar{\'i}a F Garc{\'i}a-Parajo}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2012}, volume={109 13}, pages={4869-74} }