Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence.

@article{Khan1999LateralHN,
  title={Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence.},
  author={Arshad M. Khan and Margarita C Curr{\'a}s and Jennifer Dao and Faizi A Jamal and Chuck A Turkowski and Rishi K Goel and Elizabeth Rachel Gillard and Stefany D Wolfsohn and B. Glenn Stanley},
  journal={The American journal of physiology},
  year={1999},
  volume={276 3 Pt 2},
  pages={R880-91}
}
Cells within the lateral hypothalamic area (LHA) are important in eating control. Glutamate or its analogs, kainic acid (KA) and N-methyl-d-aspartate (NMDA), elicit intense eating when microinjected there, and, conversely, LHA-administered NMDA receptor antagonists suppress deprivation- and NMDA-elicited eating. The subunit composition of LHA NMDA receptors (NMDA-Rs) mediating feeding, however, has not yet been determined. Identifying this is important, because distinct second messengers… CONTINUE READING