Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection.

@article{Tufariello2003LatentTM,
  title={Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection.},
  author={Joann M. Tufariello and John Chan and JoAnne L. Flynn},
  journal={The Lancet. Infectious diseases},
  year={2003},
  volume={3 9},
  pages={578-90}
}
Most people infected with Mycobacterium tuberculosis contain the initial infection and develop latent tuberculosis. This state is characterised by evidence of an immune response against the bacterium (a positive tuberculin skin test) but no signs of active infection. It can be maintained for the lifetime of the infected person. However, reactivation of latent infection occurs in about 10% of infected individuals, leading to active and contagious tuberculosis. An estimated 2 billion people… CONTINUE READING