Latent membrane protein 1 of Epstein-Barr virus plays an important role in the serum starvation resistance of Epstein-Barr virus-immortalized B lymphocytes.

@article{Park2004LatentMP,
  title={Latent membrane protein 1 of Epstein-Barr virus plays an important role in the serum starvation resistance of Epstein-Barr virus-immortalized B lymphocytes.},
  author={Chan-Hee Park and Hak-Ryul Kim and Ju Kim and Sun-Hee Jang and Kyung-Yeol Lee and Gook-Hyun Chung and Yong-Suk Jang},
  journal={Journal of cellular biochemistry},
  year={2004},
  volume={91 4},
  pages={
          777-85
        }
}
  • Chan-Hee Park, Hak-Ryul Kim, +4 authors Yong-Suk Jang
  • Published in
    Journal of cellular…
    2004
  • Biology, Medicine
  • We have previously shown that SNU-1103, which is a latency type III Epstein-Barr virus (EBV)-transformed lymphoblastoid cell line (LCL) that was developed from a Korean cancer patient, resists serum starvation-induced G(1) arrest. In this study, we examined the role of latent membrane protein-1 (LMP-1) in serum starvation resistance, since LMP-1 is known to be essential for EBV-mediated immortalization of human B lymphocytes. The LMP-1 gene from SNU-1103 was introduced into the EBV-negative… CONTINUE READING

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