Latent autoimmune hepatitis triggered during interferon therapy in patients with chronic hepatitis C.

@article{GarcaBuey1995LatentAH,
  title={Latent autoimmune hepatitis triggered during interferon therapy in patients with chronic hepatitis C.},
  author={Luisa C Garc{\'i}a-Buey and Carmelo Garc{\'i}a-Monz{\'o}n and S. Fernando Rodriguez and Mar{\'i}a Jes{\'u}s Borque and Asunci{\'o}n Garc{\'i}a-S{\'a}nchez and R. M. Rodriguez Iglesias and M A DeCastro and Fernando Mateos and Jose L Vicario and Antonio Balas},
  journal={Gastroenterology},
  year={1995},
  volume={108 6},
  pages={1770-7}
}
BACKGROUND/AIMS Interferon can induce autoantibodies and autoimmune reactions. This study reviewed the clinical, serological, and HLA phenotypical features of patients who developed autoimmune hepatitis during interferon therapy for chronic hepatitis C, analyzing their response to immunosuppressive treatment. METHODS The diagnosis of chronic hepatitis C was based on positivity for viral RNA and a liver biopsy specimen obtained before interferon treatment. Sera were tested for autoantibodies… CONTINUE READING