Latent antigen vaccination in a model gammaherpesvirus infection.

@article{Usherwood2001LatentAV,
  title={Latent antigen vaccination in a model gammaherpesvirus infection.},
  author={Edward J. Usherwood and Kelly Anne Ward and Marcia A Blackman and J. P. Stewart and David L. Woodland},
  journal={Journal of virology},
  year={2001},
  volume={75 17},
  pages={
          8283-8
        }
}
Vaccines that can reduce the load of latent gammaherpesvirus infections are eagerly sought. One attractive strategy is vaccination against latency-associated proteins, which may increase the efficiency with which T cells recognize and eliminate latently infected cells. However, due to the lack of tractable animal model systems, the effect of latent-antigen vaccination on gammaherpesvirus latency is not known. Here we use the murine gammaherpesvirus model to investigate the impact of vaccination… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8(+) T lymphocytes.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1999
VIEW 4 EXCERPTS