Latent adenoviral infection modifies the steroid response in allergic lung inflammation.

@article{Yamada2000LatentAI,
  title={Latent adenoviral infection modifies the steroid response in allergic lung inflammation.},
  author={Kohichi Yamada and W. Mark Elliott and Shizu Hayashi and Ralph Brattsand and Carmichael Roberts and Timothy Z. Vitalis and James C. Hogg},
  journal={The Journal of allergy and clinical immunology},
  year={2000},
  volume={106 5},
  pages={
          844-51
        }
}
BACKGROUND Steroid-resistant asthma develops after adenoviral bronchiolitis. OBJECTIVE We sought to determine the effect of steroids on allergic lung inflammation in the presence of latent adenoviral infection. METHODS Guinea pigs with latent adenoviral (n = 12) or sham (n = 12) infections were sensitized and challenged with ovalbumin (OA) or sham sensitized and challenged with saline solution. The effect of steroids (20 mg/kg administered intraperitoneally) on OA-induced lung inflammation… CONTINUE READING

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