Latent TGF-beta binding proteins.

  title={Latent TGF-beta binding proteins.},
  author={Vesna Todorovic and V. Jurukovski and Yu-guang Chen and Laura Fontana and Branka Brukner Dabovi{\'c} and Daniel B. Rifkin},
  journal={The international journal of biochemistry & cell biology},
  volume={37 1},
Latent TGF-beta binding proteins are multidomain proteins with a common, highly repetitive structural organization and partially overlapping expression patterns. Latent TGF-beta binding protein-1, -3 and -4 bind latent TGF-beta. TGF-betas are normally secreted as latent complexes, consisting of the mature TGF-beta dimer non-covalently bound to its processed propeptide dimer plus a latent TGF-beta binding protein. The latent TGF-beta binding protein is covalently bound to the propeptide. These… CONTINUE READING

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