Latent Multi-drug Resistant Tuberculosis: An Unaddressed Problem

  title={Latent Multi-drug Resistant Tuberculosis: An Unaddressed Problem},
  author={Mishra Gyanshankar and M Nadaf Jasmin},
It is estimated that three of every 1,000 individuals worldwide have latent Multidrug-Resistant Tuberculosis (MDR-TB) infection. Management of latent MDR-TB is an integral component in our strategies targeting global TB elimination. 



Evaluation of the Effect of Treatment of Latent Tuberculosis Infection on QuantiFERON-TB Gold Assay Results

To evaluate the utility of the QuantiFERON-TB Gold assay for monitoring latent tuberculosis treatment efficacy, the assay was performed serially for healthcare workers receiving isoniazid therapy and cellular proliferation assays revealed persistently strong purified protein derivative responses.

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline

New recommendations are made for the choice and number of drugs in a regimen, the duration of intensive and continuation phases, and the role of injectable drugs for MDR-TB.

Systematic Review, Meta-analysis, and Cost-effectiveness of Treatment of Latent Tuberculosis to Reduce Progression to Multidrug-Resistant Tuberculosis

  • S. MarksS. MaseS. Morris
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2017
A systematic review of studies published 1 January 1994-31 December 2014 found a reduced risk of TB incidence with treatment for MDR-LTBI, suggesting effectiveness in prevention of progression to MDR -TB, and confirmed cost-effectiveness.

MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network.

Toman's Tuberculosis--Case Detection, Treatment, and Monitoring: Questions and Answers

The second edition of this practical, authoritative reference book provides a rational basis for the diagnosis and management of tuberculosis.

Undernutrition & tuberculosis in India: Situation analysis & the way forward

Nutritional supplementation in patients with TB is associated with faster sputum conversion, higher cure and treatment completion rates, significant gain in body weight and body composition as well as better performance status.

The Industrial Revolution and the decline in death rates from tuberculosis.

  • J. Murray
  • Economics
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
  • 2015

Drug-Resistant Tuberculosis: A Survival Guide for Clinicians

  • Curry International Tuberculosis Center and California Department of Public Health
  • 2016

The global burden of multi-drug resistant latent Tuberculosis: recent trends and estimates using mathematical modelling

  • Lancet Infect Dis
  • 2019

What is the “fall and rise” phenomenon and the “sequential regimen

  • 2nd ed. Geneva, Switzerland: World Health Organization
  • 2004