Latency as a function of intensity in auditory neurons: influences of central processing

  title={Latency as a function of intensity in auditory neurons: influences of central processing},
  author={Achim Klug and Asma Khan and R. Michael Burger and Eric E Bauer and Laura M. Hurley and Lichuan Yang and Benedikt Grothe and Michele B. Halvorsen and Thomas J. Park},
  journal={Hearing Research},

Figures and Tables from this paper

Corticofugal modulation of the paradoxical latency shifts of inferior collicular neurons.

The findings indicate that corticofugal feedback is involved in shaping the spectrotemporal patterns of responses of subcortical auditory neurons presumably through inhibition.

Serotonin Shifts First-Spike Latencies of Inferior Colliculus Neurons

The results support the general conclusion that changes in latency are an important part of the neuromodulatory repertoire of serotonin within the auditory system and show that serotonin can change latency either in conjunction with broad changes in other aspects of neuronal excitability or in highly specific ways.

Leading inhibition to neural oscillation is important for time-domain processing in the auditory midbrain.

In response to paired sound pulses, PLS neurons exhibited delay-dependent response suppression, confirming that high-threshold leading inhibition was responsible for PLS and its role in time-domain processing.

Ongoing Temporal Coding of a Stochastic Stimulus as a Function of Intensity: Time-Intensity Trading

It is found that changes in intensity cause small but systematic shifts in the ongoing timing of responses in the auditory nerve, generally but not always resulting in shorter delays between stimulus onset and neural response for increasing intensity.

Oscillation May Play a Role in Time Domain Central Auditory Processing

The results suggest that neural oscillation in combination with ordinary inhibition may be responsible for the creation of PLSs shown previously to be important for temporal information processing.

A unifying basis of auditory thresholds based on temporal summation

  • P. HeilHeinrich Neubauer
  • Physics, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2003
It is demonstrated that cortical and perceptual responses are based on integration of the pressure envelope of the sound, as it was previously shown for AN fibers, rather than on intensity, which resolves the resolution–integration paradox.

Mechanisms of spectral and temporal integration in the mustached bat inferior colliculus

This review describes mechanisms and circuitry underlying combination-sensitive response properties in the auditory brainstem and midbrain. Combination-sensitive neurons, performing a type of

Effects of sound intensity on temporal properties of inhibition in the pallid bat auditory cortex

The interactions between two sound parameters in shaping sideband inhibition: intensity and time were investigated, suggesting that the relative magnitude of excitatory and inhibitory inputs shape arrival time of inhibition and FM sweep rate and direction selectivity.

Adaptation and spectral enhancement at auditory temporal perceptual boundaries - Measurements via temporal precision of auditory brainstem responses

Whether adaptation and the precision of temporal coding in the auditory periphery reproduce general perceptual boundaries in the time domain near 20, 100, and 400 ms ISIs, the physiological origin of which are unknown is studied.



On determinants of first‐spike latency in auditory cortex

This threshold model for auditory cortex neurones and by varying the amplitude and rise time of tonal stimuli, that this threshold model is inadequate to account for the observed latency changes, particularly when adaptive processes are taken into account is demonstrated.

Interaural Intensity Difference Processing in Auditory Midbrain Neurons: Effects of a Transient Early Inhibitory Input

Evidence is presented that a response pattern is created within the inferior colliculus of the Free-tailed bat that is partially inhibited with very short stimuli, such as simulated bat echolocation calls that invoked only the initial, IID-sensitive component.

Latency of unit responses in cochlear nucleus determined in two different ways.

It is concluded that the latency values of the step response represent the true sum of synaptic and axon dendritical propagation delay, whereas the latency of the responses to tone bursts also includes the temporal summation at the synaptic level.

First-spike timing of auditory-nerve fibers and comparison with auditory cortex.

The data suggest that the basic characteristics of the latency-acceleration functions of transient onset responses seen in cortex are generated at inner hair cell-AN fiber synapses.

Auditory cortical onset responses revisited. II. Response strength.

  • P. Heil
  • Physics
    Journal of neurophysiology
  • 1997
The present findings seriously question the usefulness of the spike count-level function and measures derived from it, such as threshold SPL, dynamic range, best SPL, or degree of nonmonotonicity.

Possible neural mechanisms of target distance coding in auditory system of the echolocating bat Myotis lucifugus.

Analysis of responses to single FM pulses of varying amplitude revealed another novel response property, which has been termed the paradoxical latency shift, which appears to be related to the twin-peaked complex nonmonotonic response function.

Encoding timing and intensity in the ventral cochlear nucleus of the cat.

A comparison of spontaneous firing rate and saturation firing rate of PLN units with auditory nerve fibers suggest thatPLN units receive one to four auditory nerve fiber inputs, and OC units are candidates for encoding intensity.

GABA shapes a topographic organization of response latency in the mustache bat's inferior colliculus

  • T. ParkG. Pollak
  • Biology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1993
A wide range of latencies could provide the large latency differences necessary for the coincidence detectors in the medial geniculate body tuned to signals separated by up to 20 msec.

Latency of Action Potentials in the Cochlea of Guinea Pig

The latency of the well‐synchronized whole‐nerve action potential (AP) in the cochlea of the guinea pig includes both neural and traveling‐wave delays. The latency varies with the intensity and with