Late switch for post-tetanic potentiation: once again it's Ca2+. Focus on "An increase in calcium influx contributes to post-tetanic potentiation at the rat calyx of Held synapse".


Many prior studies have documented the role of calcium in the induction of posttetanic potentiation (PTP). In this issue of the Journal of Neurophysiology (p. 2868–2876), Habets and Borst now elucidate the effect of Ca during the expression of PTP. Ingenious fine tuning of the Ca imaging allowed them to measure Ca in a largely unperturbed system: the calyx… (More)


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