Late relapses in acute myeloid leukemia: analysis of characteristics and outcome.

@article{Verma2010LateRI,
  title={Late relapses in acute myeloid leukemia: analysis of characteristics and outcome.},
  author={Dushyant Verma and Hagop A Kantarjian and Stefan H Faderl and Susan M O'Brien and Sherry M Pierce and Khanh Duy Vu and Emil J. Freireich and Michael J Keating and Jorge E. Cortes and Farhad Ravandi},
  journal={Leukemia & lymphoma},
  year={2010},
  volume={51 5},
  pages={778-82}
}
Relapse after 5 years of complete remission (CR) is uncommon in acute myeloid leukemia (AML). Among 2347 patients seen between 1980 and 2008, 1366 achieved CR; 942 relapsed. Eleven (1.16% of all relapses) relapsed after a CR of >5 years. The median age was 66 years (range, 37-79). Initial therapy was cytarabine plus anthracycline in six, amsacrine-based in three, and other in two. The median CR1 duration was 81 months (range, 60-137). At relapse, the karyotype was different from the initial… CONTINUE READING