Late onset parkinsonian syndrome in Hallervorden-Spatz disease.

@article{Alberca1987LateOP,
  title={Late onset parkinsonian syndrome in Hallervorden-Spatz disease.},
  author={Rom{\'a}n Alberca and Ester Rafel and Isidoro Chinch{\'o}n and Javier Vadillo and Alejandro Navarro},
  journal={Journal of Neurology, Neurosurgery & Psychiatry},
  year={1987},
  volume={50},
  pages={1665 - 1668}
}
  • Román Alberca, Ester Rafel, +2 authors Alejandro Navarro
  • Published 1987
  • Medicine
  • Journal of Neurology, Neurosurgery & Psychiatry
  • Two siblings, from consanguineous parents, developed in their twenties a Parkinsonian syndrome. In the elder, the disease evolved for 13 years and the necropsic study was diagnostic of Hallervorden-Spatz disease. The younger sibling is severely affected after 12 years of the disorder. Several CT and one MR studies done in this patient during the last 4 years have been normal. Ultrastructural studies of the bone marrow histiocytes and blood lymphocytes disclosed peculiar inclusions… CONTINUE READING

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