Late onset parkinsonian syndrome in Hallervorden-Spatz disease.

  title={Late onset parkinsonian syndrome in Hallervorden-Spatz disease.},
  author={Rom{\'a}n Alberca and E Rafel and Isidoro Chinch{\'o}n and Javier Vadillo and Alejandro Navarro},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={50 12},
Two siblings, from consanguineous parents, developed in their twenties a Parkinsonian syndrome. In the elder, the disease evolved for 13 years and the necropsic study was diagnostic of Hallervorden-Spatz disease. The younger sibling is severely affected after 12 years of the disorder. Several CT and one MR studies done in this patient during the last 4 years have been normal. Ultrastructural studies of the bone marrow histiocytes and blood lymphocytes disclosed peculiar inclusions… CONTINUE READING


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HallervordenSpatz disease: cysteine accumulation and cysteine dyoxygenase deficiency in the globus pallidus

TL Perry, MG Norman, VW Tong
Ann Neurol 1985;18:482-9 • 1985

Skin ultrastructural changes in Hallervorden-Spatz syndrome

ML Stover, AW Zimmerman, JO. Donaldson
Neurology • 1981

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