Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency.

@article{Kuelkens2005LateonsetND,
  title={Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency.},
  author={Sonja Kuelkens and Inga Harting and Stephanie Sauer and Johannes Zschocke and Georg Friedrich Hoffmann and Sybille Gruber and Olaf A F Bodamer and Stefan Koelker},
  journal={Neurology},
  year={2005},
  volume={64 12},
  pages={2142-4}
}
Neurologic disease in glutaryl-CoA dehydrogenase (GCDH) deficiency usually presents with acute encephalopathic crises before 2 years of age. The authors report two previously asymptomatic patients with macrocephaly presenting with progressive neurologic deterioration and a severe leukoencephalopathy during adolescence or adulthood.