Late onset hepatic failure: Clinical, serological and histological features

@article{Gimson1986LateOH,
  title={Late onset hepatic failure: Clinical, serological and histological features},
  author={Alexander E. S. Gimson and John G O'grady and Roland J Ede and Bernard C. Portmann and Roger Williams},
  journal={Hepatology},
  year={1986},
  volume={6}
}
The clinical, laboratory and histological features of 47 patients with what is defined as late onset hepatic failure are reviewed. Twenty‐five of the patients werefemale and 22 male with a median age of 45 years. Hepatic dysfunction was severe as evidenced by the prolongation of prothrombin time (median = 32 sec, range = 17 to 120 sec). In only four cases was a viral etiology proven (2 hepatitis B, 2 hepatitis A) although the similarity of the clinical features to patients with fulminant viral… 
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