Late onset hepatic failure: Clinical, serological and histological features

  title={Late onset hepatic failure: Clinical, serological and histological features},
  author={A. Gimson and J. O'Grady and R. Ede and B. Portmann and R. Williams},
  • A. Gimson, J. O'Grady, +2 authors R. Williams
  • Published 1986
  • Medicine
  • Hepatology
  • The clinical, laboratory and histological features of 47 patients with what is defined as late onset hepatic failure are reviewed. Twenty‐five of the patients werefemale and 22 male with a median age of 45 years. Hepatic dysfunction was severe as evidenced by the prolongation of prothrombin time (median = 32 sec, range = 17 to 120 sec). In only four cases was a viral etiology proven (2 hepatitis B, 2 hepatitis A) although the similarity of the clinical features to patients with fulminant viral… CONTINUE READING
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