Late-onset circulatory dysfunction of premature infants and late-onset periventricular leukomalacia.

@article{Kobayashi2008LateonsetCD,
  title={Late-onset circulatory dysfunction of premature infants and late-onset periventricular leukomalacia.},
  author={Satoru Kobayashi and Shinji Fujimoto and Norihisa Koyama and Sumio Fukuda and Toshimitsu Iwaki and Taihei Tanaka and Minoru Kokubo and Shigeru Ohki and Tohru Okanishi and Hajime Togari},
  journal={Pediatrics international : official journal of the Japan Pediatric Society},
  year={2008},
  volume={50 2},
  pages={225-31}
}
BACKGROUND The sudden appearance of hypotension and oliguria without obvious cause following stable circulation and respiration in preterm infants is frequent in Japan. Such episodes are referred to as late-onset circulatory dysfunction of premature infants (LCD). Volume expanders and inotropic agents are often ineffective against this condition, whereas i.v. steroids are significantly effective. A major problem is that cystic periventricular leukomalacia (PVL) often develops a few weeks after… CONTINUE READING
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