Late-onset bursts evoked by mossy fibre bundle stimulation in unipolar brush cells: evidence for the involvement of H- and TRP-currents.

@article{Locatelli2013LateonsetBE,
  title={Late-onset bursts evoked by mossy fibre bundle stimulation in unipolar brush cells: evidence for the involvement of H- and TRP-currents.},
  author={Francesca Locatelli and Laura Botta and Francesca Prestori and Sergio Masetto and Egidio D'Angelo},
  journal={The Journal of physiology},
  year={2013},
  volume={591 4},
  pages={899-918}
}
Synaptic transmission at central synapses has usually short latency and graded amplitude, thereby regulating threshold crossing and the probability of action potential generation. In the granular layer of the vestibulo-cerebellum, unipolar brush cells (UBCs) receive a giant synapse generating a stereotyped excitatory postsynaptic potential (EPSP)-burst complex with early-onset (∼2 ms) and high reliability. By using patch-clamp recordings in cerebellar slices of the rat vestibulo-cerebellum, we… CONTINUE READING

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