Late onset MELAS with m.3243A > G mutation and its association with aneurysm formation

@article{Zhu2017LateOM,
  title={Late onset MELAS with m.3243A > G mutation and its association with aneurysm formation},
  author={Kun Zhu and S Li and Huan Chen and Yao Wang and Miao Yu and Hongyan Wang and Wei-jie Zhao and Yun-peng Cao},
  journal={Metabolic Brain Disease},
  year={2017},
  volume={32},
  pages={1069-1072}
}
We reported a 53-year-old with late-onset mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) accompanied by aneurysm and large vessel dilations. Most studies have focused on microangiopathy causing stroke-like episodes. We report a case to describe large vessel involvement in clinical considerations, and possible mechanisms of aneurysm formation. We recommended regular angiographic examination for patients with MELAS.