Late functional and biochemical changes in mouse lung after irradiation: differential effects of WR-2721.

@article{Travis1985LateFA,
  title={Late functional and biochemical changes in mouse lung after irradiation: differential effects of WR-2721.},
  author={Elizabeth L. Travis and Marvin L. Meistrich and M V Finch-Neimeyer and Trent Watkins and I. S. Kiss},
  journal={Radiation research},
  year={1985},
  volume={103 2},
  pages={219-31}
}
The radioprotective effect of WR-2721 on late damage after whole thorax irradiation has been studied after split doses of radiation using the standard death and breathing rate assays at monthly intervals between 3 and 15 months after irradiation, as well as two biochemical measurements of injury at 15 months, hydroxyproline (HP), an indicator of tissue fibrosis, and DNA content, an indicator of tissue cellularity. A comparison of HP/lung and breaths per minute (BPM) in each dose group in the WR… CONTINUE READING