Late Retinal Progenitor Cells Show Intrinsic Limitations in the Production of Cell Types and the Kinetics of Opsin Synthesis

@article{Belliveau2000LateRP,
  title={Late Retinal Progenitor Cells Show Intrinsic Limitations in the Production of Cell Types and the Kinetics of Opsin Synthesis},
  author={Michel J. Belliveau and Tracy L Young and Constance L. Cepko},
  journal={The Journal of Neuroscience},
  year={2000},
  volume={20},
  pages={2247 - 2254}
}
The seven major cell classes of the vertebrate neural retina arise from a pool of multipotent progenitor cells. Several studies suggest a model of retinal development in which both the environment and the progenitor cells themselves change over time (Cepko et al., 1996). To test this model, we used a reaggregate culture system in which a labeled population of progenitor cells from the postnatal rat retina were cultured with an excess of embryonic retinal cells. The labeled cells were then… Expand
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