Late Breaking Abstract - Responder phenotyping using functional respiratory imaging (FRI) in IPF patients treated with anti-CGTG monoclonal antibody FG3019

@article{Mussche2017LateBA,
  title={Late Breaking Abstract - Responder phenotyping using functional respiratory imaging (FRI) in IPF patients treated with anti-CGTG monoclonal antibody FG3019},
  author={Charles Mussche and Cedric Van Holsbeke and Jan De Backer and Wim Vos and Maarten Lanclus and Benjamin Mignot and Wilfried A. De Backer and Johan Clukers and Seth Porter and Elias Kouchakji and Eduard Gorina and Jonathan G. Goldin},
  journal={European Respiratory Journal},
  year={2017},
  volume={50}
}
Aims and objectives To identify baseline FRI parameters that predict changes in FVC and fibrosis after 48w of treatment with FG3019 Methods: In this open label study, 66 IPF patients (67.9±7.0 years) completed 48 weeks of treatment with an anti-CTGF monoclonal antibody. Pulmonary function was assessed every 12 weeks and HRCT scans (TLC and RV) were taken at baseline and after 24 and 48w. Machine learning algorithms were used on the baseline FRI parameters to obtain accurate predictions of… Expand
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