Latarcins: versatile spider venom peptides

@article{Dubovskii2015LatarcinsVS,
  title={Latarcins: versatile spider venom peptides},
  author={Peter V. Dubovskii and Alexander A. Vassilevski and Sergey A Kozlov and Alexey V. Feofanov and Eugene V. Grishin and Roman G. Efremov},
  journal={Cellular and Molecular Life Sciences},
  year={2015},
  volume={72},
  pages={4501-4522}
}
Arthropod venoms feature the presence of cytolytic peptides believed to act synergetically with neurotoxins to paralyze prey or deter aggressors. Many of them are linear, i.e., lack disulfide bonds. When isolated from the venom, or obtained by other means, these peptides exhibit common properties. They are cationic; being mostly disordered in aqueous solution, assume amphiphilic α-helical structure in contact with lipid membranes; and exhibit general cytotoxicity, including antifungal… Expand
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