Latanoprost exerts neuroprotective activity in vitro and in vivo.

@article{Drago2001LatanoprostEN,
  title={Latanoprost exerts neuroprotective activity in vitro and in vivo.},
  author={F. Drago and S. Valzelli and I. Emmi and A. Marino and C. C. Scalia and V. Marino},
  journal={Experimental eye research},
  year={2001},
  volume={72 4},
  pages={
          479-86
        }
}
Prostaglandins may influence cyclo-oxygenase (COX-2) and nitric oxide (NO) synthase activity, thus interfering with ischemia-induced neurotoxic processes. The prostaglandin synthetic derivative, latanoprost was tested in different in vivo and in vitro models of neuronal damage in order to study its influence on these processes. Ischemia was induced in rats by bilateral occlusion of the carotid arteries for 30 min. Latanoprost (0.01 mg x kg(-1)per die, i.p. for 3 days) or the ionotropic… Expand
Latanoprost protects rat retinal ganglion cells from apoptosis in vitro and in vivo.
Bimatoprost protects retinal neuronal damage via Akt pathway.
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