Lasp-2 expression, localization, and ligand interactions: a new Z-disc scaffolding protein.

@article{Zieseniss2008Lasp2EL,
  title={Lasp-2 expression, localization, and ligand interactions: a new Z-disc scaffolding protein.},
  author={Anke Zieseniss and Asako Goi Terasaki and Carol C. Gregorio},
  journal={Cell motility and the cytoskeleton},
  year={2008},
  volume={65 1},
  pages={59-72}
}
The nebulin family of actin-binding proteins plays an important role in actin filament dynamics in a variety of cells including striated muscle. We report here the identification of a new striated muscle Z-disc associated protein: lasp-2 (LIM and SH3 domain protein-2). Lasp-2 is the most recently identified member of the nebulin family. To evaluate the role of lasp-2 in striated muscle, lasp-2 gene expression and localization were studied in chick and mouse tissue, as well as in primary… CONTINUE READING

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