Laser microdissection and pressure catapulting of single human motor neurons for RNA editing analysis.

Abstract

Glutamate is the major excitatory neurotransmitter in the mammalian nervous system. The properties of their ionotropic glutamate receptors largely determine how different neurons respond to glutamate. RNA editing in pre-mRNAs encoding subunits of glutamate receptors, particularly the GluR 2 subunit of AMPA receptors, controls calcium permeability, response… (More)
DOI: 10.1007/978-1-61779-018-8_4

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