Laser-mediated activation of human retinal pigment epithelial cells and concomitant release of matrix metalloproteinases.

@article{Zhang2012LasermediatedAO,
  title={Laser-mediated activation of human retinal pigment epithelial cells and concomitant release of matrix metalloproteinases.},
  author={Jin Zhang and Yue Fang Sun and Ali Aijaz Hussain and John Marshall},
  journal={Investigative ophthalmology & visual science},
  year={2012},
  volume={53 6},
  pages={2928-37}
}
PURPOSE To investigate cellular dynamics and associated matrix metalloproteinase (MMP) release patterns of human retinal pigment epithelium (RPE) cells subsequent to irradiation by nanosecond pulsed laser at energy levels below visual threshold. METHODS Following a stabilization period, human RPE-Bruch's-choroid explants were irradiated with a nanosecond laser system (Q-switched, frequency doubled YAG laser, 532 nm), using a 400 μm spot size with a discontinuous energy distribution and total… CONTINUE READING
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