• Corpus ID: 8948162

Laser light-field fusion for wide-field lensfree on-chip phase contrast nanoscopy

@article{Kazemzadeh2016LaserLF,
  title={Laser light-field fusion for wide-field lensfree on-chip phase contrast nanoscopy},
  author={Farnoud Kazemzadeh and Alexander Wong},
  journal={ArXiv},
  year={2016},
  volume={abs/1604.08145}
}
Wide-field lensfree on-chip microscopy, which leverages holography principles to capture interferometric light-field encodings without lenses, is an emerging imaging modality with widespread interest given the large field-of-view compared to lens-based techniques. In this study, we introduce the idea of laser light-field fusion for lensfree on-chip phase contrast nanoscopy, where interferometric laser light-field encodings acquired using an on-chip setup with laser pulsations at different… 

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References

SHOWING 1-10 OF 34 REFERENCES

Lens-free spectral light-field fusion microscopy for contrast- and resolution-enhanced imaging of biological specimens.

Experimental results demonstrated that the LSLFM system provided SNR improvements of 6-12 dB, as well as a six-fold improvement in the dispersion index (DI), over that achieved using a single-channel, resolution-enhancing lens-free deconvolution microscopy system or its multi-wavelength counterpart.

Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array.

This results constitute the first-time that a lensfree on-chip microscope has successfully imaged malaria parasites and would be important for global health problems such as diagnosis of infectious diseases in remote locations.

Synthetic aperture-based on-chip microscopy

Wide field-of-view (FOV) and high-resolution imaging requires microscopy modalities to have large space-bandwidth products. Lensfree on-chip microscopy decouples resolution from FOV and can achieve a

Lens-free Multi-Laser Spectral Light-Field Fusion Microscopy

We present a device and method for performing lens-free spectral light-field fusion microscopy at sub-pixel resolutions while taking advantage of the large field-of-view capability. A collection of

Wide-field computational color imaging using pixel super-resolved on-chip microscopy.

This work introduces and compares the performances of two computational methods based on (1) YUV color space averaging, and (2) Dijkstra's shortest path, both of which eliminate color artifacts in reconstructed images, without compromising the spatial resolution or the wide FOV of lens-free on-chip microscopes.

Increased space-bandwidth product in pixel super-resolved lensfree on-chip microscopy

By using the two-dimensional pixel-function of an image sensor-array as an input to lens free image reconstruction, pixel-super-resolution can improve the numerical aperture of the reconstructed image by ~3 fold compared to a raw lensfree image.

Giga-Pixel Lensfree Holographic Microscopy and Tomography Using Color Image Sensors

Giga-pixel lensfree holographic microscopy and tomography using color sensor-arrays such as CMOS imagers that exhibit Bayer color filter patterns, and the proof-of-concept of this lensfree optical tomographic microscopy platform on a color CMOS image sensor is demonstrated.

Near-Field Optics: Microscopy, Spectroscopy, and Surface Modification Beyond the Diffraction Limit

The near-field optical interaction between a sharp probe and a sample of interest can be exploited to image, spectroscopically probe, or modify surfaces at a resolution inaccessible by traditional far-field techniques, resulting in a technique of considerable versatility.

Wide-field optical detection of nanoparticles using on-chip microscopy and self-assembled nanolenses.

A high-throughput, on-chip detection scheme that uses biocompatible wetting films to self-assemble aspheric liquid nanolenses around individual nanoparticles to enhance the contrast between the scattered and background light is described.

Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging.

This work introduces superresolved DIHM incoming from time and angular multiplexing of the sample spatial frequency information and yielding in the generation of a synthetic aperture (SA).