Laser and other light therapies for the treatment of acne vulgaris: systematic review

  title={Laser and other light therapies for the treatment of acne vulgaris: systematic review},
  author={F L Hamilton and Josip Car and Christopher Lyons and Milena Car and Alison M. Layton and Azeem Majeed},
  journal={British Journal of Dermatology},
Background  Acne is common and can lead to scarring of the skin, as well as to psychological distress and reduced self‐esteem. Most topical or oral treatments for acne are inconvenient and have side‐effects. Laser and other light therapies have been reported to be convenient, safe and effective in treating acne. 

Light-based treatments for acne

Long-term efficacy of light-based therapy is still lacking and careful selection of patients is necessary given its cost and discomfort, so patients whose acne is resistant to conventional treatments or who are intolerant to their side effects may be candidates for light treatment.

Laser and Light Based Therapies for Acne

Laser and light-based treatments can potentially offer a viable adjunct or even alternative to conventional topical and systemic therapeutics for treating acne vulgaris.

Treatment of Acneiform Eruptions, Acne and Acne Scars with Surgery, Lasers and Light-Based Devices

Acne is a common skin disease that affects pilosebaceous unit, and it is characterized as comedones, inflammatory papules, pustules and occasionally nodulocystic lesions. Acne scar lesions have

Light-based therapies in acne treatment

This review focuses on optical devices used in treating acne and serves to delineate the current application of various methods, including their utility and efficacy.

The pulsed‐dye laser as an adjuvant treatment modality in acne vulgaris: a randomized controlled single‐blinded trial

This data indicates that pulsed‐dye laser treatment with a high concentration of H2O can be a viable treatment for Acne vulgaris with long-term benefits.

Evaluation of the clinical efficacy of the 1450 nm laser in acne vulgaris: a randomized split‐face, investigator‐blinded clinical trial

Background  The 1450 nm laser shrinks sebaceous glands histologically, reduces seborrhoea and has been shown in numerous small uncontrolled studies to improve inflammatory acne.

Non-medical treatments for inflammatory acne vulgaris: a comprehensive review on laser, radiofrequency and microneedling

Nonmedical device-based therapies largely improve the treatment of active inflammatory acne vulgaris, especially in patients who are not compliant or eligible to consume acne medications, do not respond to these drugs over a specified period of time, or do not sustain in the remission phase.

Laser and Light-Based Treatments for Acne Vulgaris

By combining medical treatments with laser and light-based procedures in the office, dermatologists can provide patients with patients with moderate to severe acne vulgaris and show that pharmacotherapy addresses the underlying pathophysiology of acne and effectively manages most cases.

Combination of intense pulsed light and fractional CO2 laser treatments for patients with acne with inflammatory and scarring lesions

This poster presents a poster presented at the 2015 American Academy of Dermatology Congress exploring the uses of laser and light sources in cosmetic dermatology and their applications in medicine and sport.

Light therapies for acne.

The quality of the evidence was rated as very low for the comparison of light therapies, including PDT to placebo, no treatment, topical treatment or other comparators for this outcome, and the risk of bias was judged as unclear.



Topical methyl aminolaevulinate photodynamic therapy for treatment of facial acne vulgaris: results of a randomized, controlled study

Preliminary experience suggests that topical methyl aminolaevulinate photodynamic therapy (MAL‐PDT) may have potential for moderate to severe acne vulgaris.

Topical aminolevulinic acid‐photodynamic therapy for the treatment of acne vulgaris

The purpose of this study was to evaluate the safety and efficacy of PDT in the treatment of acne on the face.

Topical aminolaevulinic acid‐photodynamic therapy for the treatment of acne vulgaris: a study of clinical efficacy and mechanism of action

A large number of 16‐year‐olds with acne are seeking help from a clinician, and fears over the safety and tolerance of oral isotretinoin treatments create a demand for novel treatment modalities in acne.

A Comparative study of intense pulsed light alone and its combination with photodynamic therapy for the treatment of facial acne in Asian skin

The study reported herein evaluated the effect on acne vulgaris of IPL alone and when IPL was combined with photodynamic therapy (PDT) using topical methyl aminolevulinate (MAL) in Asians.

Photodynamic therapy of acne vulgaris using methyl aminolaevulinate: a blinded, randomized, controlled trial

This poster focuses on the treatment of acne vulgaris in adolescents and young adults with atypical pimple-like symptoms and the use of corticosteroids, which are commonly used for this condition.

Blue light phototherapy in the treatment of acne

Blue light irradiation is known to be effective against acne, but the profile of a good candidate is still unclear and the benefits and risks are still unclear.

Nonablative Phototherapy for Acne Vulgaris Using the KTP 532 nm Laser

  • W. BaughWalter D Kucaba
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2005
Use of the KTP 532 nm laser for the treatment and management of acne vulgaris is both safe and effective, with positive results enduring up to 4 weeks post-treatment.

Treatment of Inflammatory Facial Acne Vulgaris with Intense Pulsed Light and Short Contact of Topical 5‐Aminolevulinic Acid: A Pilot Study

  • Prapawan Choawawanich
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2006
Short contact of topical ALA and IPL or IPL alone showed some beneficial effect in treatment of inflammatory facial acne; however, degree of improvement was better and remained longer with the combined regimen.

Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial.

The nonpurpuric pulsed dye laser therapy did not result in significant improvement of facial acne and more research is needed before this laser therapy may be recommended as an acne treatment.

Red Light Phototherapy Alone Is Effective for Acne Vulgaris: Randomized, Single‐Blinded Clinical Trial

  • D. Suh
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2007
This study shows that red light phototherapy alone can be a new therapeutic option for acne vulgaris and is shown to be significant compared to the control side.